Business Wire

DNA Script Enables Same-day q/dPCR from Design to Results with Launch of Next-generation SYNTAX Kits at AGBT

Share

Today at the Advances in Genome Biology and Technology (AGBT) Conference, DNA Script, a world leader in Enzymatic DNA Synthesis (EDS) for DNA on demand, announced the launch of the industry’s first solution to enable same-day turnaround for custom q/dPCR assays with a new generation of kits for the SYNTAX System to print both primers and probes in hours. This announcement comes two days ahead of their AGBT presentation on Wed, June 8, at 2:55pm EDT, where their founders will review recent data showcasing the new applications enabled for the SYNTAX System.

For the first time since the introduction of PCR in 1984, labs will be able to design and print q/dPCR assays, directly on their benchtops, in as little as 8 hours. The combination of increased performance, just 15 minutes of set up, rapid synthesis turnaround and complete workflow control provides labs the best value for custom modified oligos. The new kits are designed to accelerate assay development workflows in genomics, in particular for q/dPCR, NGS, ISH and FISH.

“We see this product launch as a game-changer, enabling SYNTAX customers to be done with their assays before others have even started. More than ever before, science and innovation are in a race for results, whether it is an upcoming scientific publication, a new diagnostic test or even a vaccine. Researchers need to get there faster, and we will help them to get there first,” said DNA Script CEO and co-founder Thomas Ybert, Ph.D. “With an in-house, benchtop SYNTAX System and these new kits, we are enabling our customers to replace a complex synthesis workflow with a single instrument that takes the iterative assay development process from months down to days.”

This latest generation of kits launches several new capabilities on the SYNTAX Platform:

  • Print oligos up to 80 nt in length
  • Synthesize hydrolysis probes and primers in the same run, in as little as 8 hours
  • Print oligos at a higher yield and concentration (≥7 µM and ≥600 pmol)
  • Label probes with fluorophores, quenchers and biotin

DNA Script’s SYNTAX Platform offers researchers dramatic time savings, printing primers and probes in 8 - 12 hours, as well as the best value per assay compared to leading third-party oligo service solutions in the marketplace. Early adopters of the SYNTAX platform have already leveraged on-demand synthesis to eliminate bottlenecks in the development of assays for biothreat detection, assays for rapid-response to viral outbreaks, and novel vaccines and therapies.

“The SYNTAX System is a game changer for preclinical CRO labs like ours. For the biomarker identification and gene expression profiling we do, we spend thousands of dollars a month on primers and probes and end up waiting for them to be synthesized and shipped. Having SYNTAX on site cuts our assay turnaround time, decreases our cost per assay by ~30%, and enables our lab to optimize expression assays more quickly--all of which significantly improves our bottom line," said Jonathan Wray, Managing Partner at DC3 Therapeutics. “The ease of use and excellent service and support from DNA Script enabled us to be up and running with the SYNTAX System in no time.”

As a Bronze sponsor, DNA Script is hosting a hospitality room in the Jade-Lexington Suite throughout the duration of the AGBT Conference, where attendees can see the SYNTAX System in action, demonstrating the speed of synthesizing probes and primers in-house with plug-and-play ease and automation. One-on-one demonstrations can be scheduled in advance.

DNA Script presentations at AGBT include:

  • Podium Presentation: Same-Day Enzymatic DNA Synthesis: Now Print Primers and Labeled Probes Using the SYNTAX System
    Presenters: Ybert and DNA Script CTO and co-founder Xavier Godron, Ph.D.
    Date & Time: Wed, June 8, 2:55 - 3:15 pm EDT
    Location: Main Session - Floridian Salons A-L
  • Poster Presentation (#517): Enzymatic DNA Synthesis (EDS) Allows Rapid Access to Synthetic Oligos to Produce Expression Vectors for SARS-CoV-2 Spike Variants
    Presenters: Benoit Derrien, Ph.D., Application Project Leader, DNA Script
    Date & Time: Tues, June 7, 1:30 - 3:00 pm EDT
    Location: Bonnet Creek Ballroom Salon VII-XII
  • Poster Presentation (#540): Access to Synthetic Oligos Produced by Enzymatic DNA Synthesis (EDS) Accelerated the Development of Candida glabrata Mutants During the COVID-19 Pandemic
    Presenters: Colin Clairet, Ph.D., Post-doctoral Researcher, Institut Pasteur
    Date & Time: Wed, June 8, 4:40 pm - 6:10 pm EDT
    Location: Bonnet Creek Ballroom Salon VII-XII

“Since we released the world’s first commercial access to Enzymatic DNA Synthesis via the SYNTAX Platform in the summer of 2021, we have made a number of improvements to advance benchtop DNA printing,” said Ybert. “Given the many applications, and the urgent need to perform them quickly, in-house DNA printing on demand is becoming one of the most important technologies of the 21st century.”

About DNA Script

Founded in 2014, DNA Script is a pioneering life sciences technology company developing a new, faster, more powerful and versatile way to design and manufacture nucleic acids. The company has developed an alternative to traditional DNA synthesis called Enzymatic DNA Synthesis, or EDS, enabling this technology to be accessible to labs with the first benchtop enzymatic synthesis instrument, the SYNTAX System. By putting DNA synthesis back in the lab, DNA Script aims to transform life sciences research through innovative technology that gives researchers unprecedented control and autonomy. www.dnascript.com.

To view this piece of content from cts.businesswire.com, please give your consent at the top of this page.

Contact information

Press contacts in the US
Seismic

Valerie Enes
415-692-6799
valerie@teamseismic.com

DNA Script Contact
Joleen Rau
joleen.rau@dnascript.co
publicrelations@dnascript.co

Press contact in Europe
ALIZE RP

Caroline Carmagnol
06 64 18 99 59
caroline@alizerp.com

About Business Wire

Business Wire
Business Wire
24 Martin Lane
EC4R 0DR London

+44 20 7626 1982http://www.businesswire.co.uk

(c) 2018 Business Wire, Inc., All rights reserved.

Business Wire, a Berkshire Hathaway company, is the global leader in multiplatform press release distribution.

Subscribe to releases from Business Wire

Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.

Latest releases from Business Wire

O-RAN Announces Certification and Badging Program, Next Generation Research Group, Open RAN Summit, and Results of Spring 2022 PlugFest30.6.2022 09:33:00 CEST | Press release

Since its beginning in 2018, the O-RAN ALLIANCE’s mission has been transforming Radio Access Networks towards open, intelligent, virtualized and fully interoperable RAN. Now, the O-RAN Ecosystem counts more than 340 companies and institutions from all over the world. O-RAN’s emphasis on openness is reflected in its setup as an open technical organization, according to the WTO criteria, where incumbent as well as emerging industry players or academic institutions can join and contribute. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20220630005362/en/ O-RAN ALLIANCE Industry Summit June 2022 The O-RAN ALLIANCE Industry Summit June 2022 concluded on June 29, 2022 and is now available for on-demand replay at our website. O-RAN Certification and Badging Program in cooperation with Open Test and Integration Centres (OTIC) O-RAN ALLIANCE has launched its Certification and Badging program. O-RAN certificates state that an equipment

Quorum Software Announces Next Generation Planning and Economics Partnership with Schlumberger30.6.2022 09:00:00 CEST | Press release

Quorum Software (Quorum), a global software leader dedicated to the energy industry, announced today that it has entered into an agreement with Schlumberger to jointly integrate Quorum’s industry-leading Planning Space, a business planning and petroleum economics offering, with the FDPlan field development planning solution, which is enabled by the DELFI cognitive E&P environment. The integrated solution will be offered directly by Schlumberger with Planning Space as its petroleum economics engine. As part of the agreement, Quorum will also acquire Merak planning, risk, and reserves software from Schlumberger. “Quorum and Schlumberger have developed longstanding relationships with our customers and partners over decades of serving the energy industry,” said Gene Austin, Chief Executive Officer at Quorum. “Bringing together our market-leading planning and economics solutions gives customers around the world access to the industry’s most complete technology ecosystem, backed by our team

ADVA unveils market’s first high-performance optical cesium clock30.6.2022 09:00:00 CEST | Press release

ADVA (FSE: ADV) today achieved an industry first with the introduction of its Oscilloquartz high-performance optical cesium atomic clock. The coreSync™ OSA 3300-HP is ADVA’s latest innovation in assured PNT, ushering in a new age of precise synchronization with unprecedented stability. Following ADVA’s launch of the first optical pumping timing solution two years ago, the OSA 3350 ePRC+, the OSA 3300-HP takes the technology to new levels. It has a 10-year lifetime compared to the five years offered by currently available high-performance magnetic clocks. As the market’s only high-performance optical cesium clock, the OSA 3300-HP sets a new benchmark for precision and availability, providing the resilience required for PNT assurance in critical infrastructure and empowering service providers to deliver differentiated SLA timing offerings with integrated GNSS backup. The feature-rich device has embedded Ethernet- and IP-based management as well as a user-friendly touchscreen GUI. This pr

Europ Assistance Group Chooses Akur8 to Strengthen Its Pricing Process30.6.2022 09:00:00 CEST | Press release

Europ Assistance Group and Akur8 are delighted to announce their collaboration to strengthen Europ Assistance's pricing process for its Travel Insurance and Car Assistance programs. By joining forces with one of the world's leading assistance companies, Akur8 is extending its European footprint and developing its expertise in the pricing of various insurance products. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20220610005219/en/ Specifically developed for insurers, Akur8’s solution enhances their pricing processes by automating risk modeling using Transparent Artificial Intelligence proprietary technology. Core benefits for insurers include increased predictive performance and speed-to-accuracy for higher market reactivity and immediate business impact, all while maintaining full transparency and control of the models created. In 1963, Europ Assistance invented the concept of assistance. With 24/7 assistance and an interna

Another Award for the Sturdza Family Fund30.6.2022 09:00:00 CEST | Press release

Having reached its third anniversary in December 2021 the Sturdza Family Fund and the investment team became eligible for consideration by a number of the industry’s independent rating agencies. To date, the Fund has received 4-star and 5-star Morningstar ratings (depending on the share class); a 5-Globe ‘High’ Morningstar Sustainability Rating (putting the Fund in the top 10% of all Funds within its peer group) and three of the investment team have been rated by Citywire. These all speak to the quality of the management of the Fund, particularly from a risk-adjusted perspective. We are pleased to advise therefore the Fund has received further recognition, from FundsPeople. They have classified the Sturdza Family Fund as one of their "Distinguished Investment Products of the Year" within their 2022 Fund ratings in Italy and Spain. The Sturdza Family Fund has been recognised for the consistency of the returns, with reference tovolatility versus its Morningstar-defined peer group. Additi