Business Wire

Aldena Therapeutics Selects PCI Pharma Services to Manufacture and Distribute Innovative Investigational Treatment for Dermatological Diseases


Aldena Therapeutics, a private biotech company pioneering siRNA- based therapies for dermatological indications, has chosen PCI Pharma Services (PCI), a world-leading global contract development and manufacturing organization (CDMO) to formulate, package, and distribute ALD-102, an siRNA-based investigational injectable treatment for inflammatory dermatological conditions, all under one roof at PCI’s San Diego facility. ALD-102 is currently in preclinical trials and represents the most advanced therapy in Aldena's pipeline.

Dermatological diseases affect more than 900 million people worldwide. Significant advancements in the treatment of various skin conditions and disorders have been made. However, there are still limitations and challenges in the field. With the siRNA-based approach, Aldena develops advanced and long-lasting treatments for skin conditions. CDMOs are playing a critical role in the large and small- medium pharmaceutical value chain, to bring these life-changing therapies to patients.

“We are very pleased as Aldena’s agreement with PCI has given us the integrated services and support we need to meet our ambitious research and development timelines,” said Thibaud Portal, Ph.D., CEO of Aldena. “This collaboration with PCI will be essential as we continue building our pipeline of new dermatological products targeting conditions for which there is an unmet medical need.”

PCI specializes in development and manufacturing, clinical trial services, advanced drug delivery and commercial technology services. Aldena chose PCI because of its expertise in complex formulations, and cold chain. PCI’s state-of-the-art robotic sterile fill-finish gloveless isolator platform can be used to fill various sterile medications into vials and syringes for small-to-mid size client needs. The equipment, paired with PCI’s end-to-end services and global network, comprises PCI’s Speed to Study™ offering, which drastically decreases the average turnaround time from proposal signing to the injectable product’s distribution for clinical trial use.

The Microcell Vial Filler and SA25 Aseptic Filling Workcell at PCI’s San Diego facility ensures the delivery of medicines from phase I through phase III, supporting local and global Clinical client needs. These advanced machines expedite the filling process with automation and remove the need for human intervention in a sterile environment, creating compliance advantages over standard equipment.

While there is increased demand for siRNA-based therapies in the pharmaceutical industry, only highly specialized CDMOs like PCI can manage the unique handling requirements of fragile large-molecule formulas to manufacture them safely and efficiently.

“We are proud to be one of only a few CDMOs worldwide able to offer integrated sterile fill-finish capabilities, alongside our clinical packaging facilities, to clients who are developing novel and disruptive approaches to treating disease,” said Salim Haffar, CEO of PCI Pharma Services. “Working with innovative companies like Aldena directly ladders back to our mission to provide clinical and commercial supply chain solutions to ultimately improve patients’ lives.”

To better support its clients throughout the world, PCI has recently invested in expansions in Rockford, IL, and Tredegar, Wales, as well as established new facilities in Bedford, NH, and Boston, MA.

About Aldena

Aldena Therapeutics is a Boston, Lausanne, and London-based biotechnology company focusing on siRNA-based treatments for patients suffering from dermatological diseases. The Company was co- founded by Prof. John Harris (MD, PhD, Professor and Chair of Dermatology at UMass Chan Medical School), Prof. Mark Prausnitz (PhD, Regents' Professor at Georgia Institute of Technology) and Dr Andrew Tadros (MD, PhD) and is backed by international investment firm, Medicxi. Aldena Therapeutics has been led since its inception by dermatology specialist, CEO, Thibaud Portal, PhD, who previously led the Prescription Medicines business and strategy of Galderma SA after several senior R&D roles and co- founded several dermatology focused start-up companies. Aldena is pursuing multiple innovative programs and is currently initiating the IND-enabling GLP nonclinical program for its lead projects.

About PCI Pharma Services

PCI is a leading global CDMO, providing clients with integrated end-to-end drug development, manufacturing and packaging capabilities that increase their products’ speed to market and opportunities for commercial success. PCI brings the proven experience that comes with more than 90 successful product launches each year and over five decades in the healthcare services business. We currently have 30 sites across seven countries (Australia, Canada, U.S., Ireland, Wales, Germany and Spain) and over 5,000 employees that work to bring life-changing therapies to patients. Leading technology and continued investment enable us to address global drug development needs throughout the entire product life cycle – from manufacturing capabilities through the clinical trial supply chain and into commercialization. Our clients view us as an extension of their business and a collaborative partner with the shared goal of improving patients’ lives. For more information, please visit

To view this piece of content from, please give your consent at the top of this page.

Contact information

Ty Guzman-Touchberry, WE Communications / +1-212-551-4877

About Business Wire

Business Wire
Business Wire
24 Martin Lane
EC4R 0DR London

+44 20 7626 1982

(c) 2018 Business Wire, Inc., All rights reserved.

Business Wire, a Berkshire Hathaway company, is the global leader in multiplatform press release distribution.

Subscribe to releases from Business Wire

Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.

Latest releases from Business Wire

Global donors pledge over US$777 million to defeat neglected tropical diseases and improve the lives of 1.6 billion people at the Reaching the Last Mile Forum at COP283.12.2023 15:40:00 CET | Press release

Global donors at the 2023 Reaching the Last Mile Forum today pledged a collective US$777.2 million to help control, eliminate, and eradicate neglected tropical diseases (NTDs), in a landmark push to accelerate progress towards achieving the goals outlined in the World Health Organization’s 2030 roadmap on NTDs. This press release features multimedia. View the full release here: Uniting efforts with NTD-endemic countries, donors answered the urgent call to step up the fight against NTDs in the face of climate change, and to work together to improve the lives of the 1.6 billion people worldwide affected by these devastating yet preventable diseases. The pledging event was hosted by Reaching the Last Mile (RLM), the global health initiative driven by the philanthropy of His Highness Sheikh Mohamed Bin Zayed Al Nahyan, President of the UAE, in partnership with the Bill & Melinda Gates Foundation. The forum took place on the first ev

Sharjah Celebrates the UAE’s 52nd Union Day3.12.2023 09:22:00 CET | Press release

Sharjah concluded the 52nd Union Day celebrations, which lasted for 12 days, with wide participation from all segments of society including government entities, private sector institutions, Emiratis, international residents, and visitors to the emirate. This press release features multimedia. View the full release here: From the Union Day celebration in Sharjah (Photo 1: AETOSWire) Over 200 activities organized by the Sharjah National Day Celebrations Committee took place in the cities of Sharjah, Mleiha, Dibba Al Hosn, Khorfakkan, Kalba, Al Bataeh, Al Mudam, Al Dhaid, and Al Hamriyah. Celebrations also took place in cultural and tourist areas as Al Dhaid Fort, the heritage villages in Al Hamriyah, Mleiha, Kalba. Other locations included Wadi Al Hilo, the National Park in Sharjah, Al Hosn Island Canal, Khorfakkan Amphitheatre, Kalba Lake, and Al Bataeh Public Park. His Excellency Khalid Jasim Al Midfa, Chairman of the Sharjah Na

IFRC-DREF calls on global donors to help the world ‘Stand Tall’ in the face of accelerating humanitarian need - supporting smarter and faster disaster relief3.12.2023 01:01:00 CET | Press release

The International Federation of Red Cross and Red Crescent Societies (IFRC) has launched a new campaign to address rapidly escalating climate driven humanitarian crises. It calls on global governments and international donors to support local emergency responders and disaster hit communities - helping them to Stand Tall with smarter and faster humanitarian funding. This press release features multimedia. View the full release here: Stand Tall in the face of disaster with IFRC-DREF Insurance. (Photo: Business Wire) The IFRC’s Disaster Response Emergency Fund (IFRC-DREF) is the quickest, most efficient and most transparent way of getting funding directly to local National Societies — both before and immediately after a crisis hits. Yet it faces growing pressure to anticipate and respond to multiple, simultaneous and complex crises around the world as a result of climate change. Today, 3.6 billion people live in areas highly suscep

11 Winners Recognised at Zayed Sustainability Prize Awards Ceremony held during COP28 UAE2.12.2023 03:15:00 CET | Press release

His Highness Sheikh Mohamed bin Zayed Al Nahyan, President of the UAE, today awarded the winners of the Zayed Sustainability Prize, the UAE’s pioneering global award in sustainability and humanitarianism, during a ceremony held at COP28 UAE in Expo City Dubai. This press release features multimedia. View the full release here: 11 winners of the Zayed Sustainability Prize Recognised at COP28 (Photo: AETOSWire) The Ceremony was attended by numerous heads of delegations participating in COP28, ministers, senior government officials, and Prize winners and finalists. His Highness congratulated the winners, praising their efforts in promoting sustainability and encouraging them to continue their important contributions in this field. His Highness emphasised that the UAE is steadfast in building upon its established legacy in sustainability, a foundation laid by the country’s Founding Father, the late Sheikh Zayed bin Sultan Al Nahyan.

Zextras Introduces Carbonio - A Private Digital Workplace1.12.2023 16:07:00 CET | Press release

Zextras, the leading email and collaboration solutions provider, introduced Carbonio - a private digital workplace for the public sector and regulated industries. Carbonio emerges as an exceptional solution for the public sector, enabling them to implement an extensive digital workspace for their internal teams and stakeholders. Delivering a suite of features that are not only comprehensive but also fully customizable, from emails and calendars to video meetings and file storage, Carbonio allows for superior adaptation to any unique technical requirements or business objectives. It is equally enticing for regulated industries to enhance their operations by providing secure software solutions tailored to meet the distinct security needs of their country and respective states. The platform is rooted in robust compliance with global data protection regulations, including the European General Data Protection Regulation (GDPR). This fosters a secure digital environment for users, ensuring t