Autologous immune-cell therapy, practiced in Japan, now helping Vinmec Hospital, treat cancer patients in Hanoi, Vietnam, after technology transfer by GN Corporation
Treatment of cancer using one’s own immune cells, natural killer (NK) cells and T-cells, called autologous immune enhancement cell therapy (AIET) administered along with conventional chemotherapy, radiotherapy and surgery, practiced in Japan for long is now offered in Vinmec hospital, Hanoi, Vietnam, following technology transfer by GN Corporation. Cancer patients from neighboring countries are now visiting Vinmec hospital for this treatment. Autologous immune-cell therapy, regulated by the regenerative medicine law in Japan, uses lab-expanded autologous immune cells, without animal proteins or genetic manipulation.
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NK cells and T-cells in vitro culture method, without feeder cells or animal serum or genetic manipulation, for immune-cell therapy to cancer patients developed and practiced in Japan was tech-transferred to Vinmec Hospital, Hanoi, Vietnam, which was accomplished in phases viz., (i) Cell processing facility infrastructure and equipment advisory, (ii) Training of biotechnologists from Vietnam in Japan, (iii) On-site, technical support in Vinmec hospital lab by Japanese experts (iv) Educational seminars to physicians, oncologists and (v) Interaction with regulatory authority in Japan, the PMDA and MHLW; spearheaded by GNC Japan. Immune-cell therapy with Thermotron RF8-EX radiofrequency hyperthermia, when added to conventional cancer treatment, yields increase in survival of cancer patients. These safety proven treatments practiced for long in Japan to manage most of the solid tumours are of interest to many cancer hospitals overseas to add them to their existing oncology services. (Graphic: Business Wire)
Benefits of AIET & hyperthermia: Whileincrease in survival rate in cancer patients is reported by adding immune-cell therapy to conventional treatment regimen, the Hyperthermia system developed in Japan further improves outcome of cancer treatment as it targets the cancer cells, vulnerable to damage at a higher temperature of 42 Deg Celsius.To propagate these add-on cancer treatments to overseas hospitals, GNC Japan is collaborating with Yamamoto Vinita, manufacturers of Thermotron, the first hyperthermia equipment to treat malignant tumors, approved in Japan, installed in more than 300 hospitals in six countries, till date. The latest Thermotron-RF8-EX version is a stand-alone system with Eight MHZ radiofrequency, uses electrodes of different sizes in combination to treat superficial and deep-seated solid tumors of the entire body except eye and brain.
Thermotron RF8-EX Salient features:
- Enhances the beneficial effects of chemotherapy and radiotherapy
- Improves immunity and also the quality of life of cancer patients
- No radiation and therefore no need for any shielding
- Easy raise of temperature of the target lesion region
- Safety track record since 1980 in more the 300 cancer hospitals
Hospitals in Japan offering these cancer therapies receive patients from abroad for treatment. Recently overseas cancer hospitals have started showing interest in adding these two therapies to their existing systems for cancer treatment in clinical oncology services.
Accomplishments of GN Corporation, in adding value to Japanese technologies by inter-disciplinary interaction, developing novel healthcare solutions and global propagation were featured by Govt of Japan in the official YouTube channel of the prime minister’s office of Japan, JETRO Invest in Japan portal and a feature story sponsored by Govt of Japan in Bloomberg.
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Samuel JK Abraham
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