GlobeNewswire by notified

Ultimovacs Receives Notice of Allowance on US Patent on Vaccine-Checkpoint Inhibitor Combinations

Share
  • Extends protection for UV1 vaccine-checkpoint inhibitor combinations until at least 2037
  • Covers UV1 with CTLA-4, PD-1 or PD-L1 checkpoint inhibitors

Oslo, 22 April 2022: Ultimovacs ASA ("Ultimovacs") (OSE ULTI), a clinical stage leader in immune stimulatory vaccines for cancer, received a Notice of Allowance from the United States Patent and Trademarks Office (USPTO) concerning its US patent application 16/306,352 on the use of vaccine-checkpoint inhibitor combinations to treat cancer. Subject to grant formalities, it is expected that a patent will issue with a patent term up to at least June 2037. Ultimovacs has similar patent applications pending in other territories worldwide, including Europe, Japan, Canada and Australia.

The scope of the patent, when issued, will cover cancer treatments that include the UV1 peptide vaccine in combination with an anti-CTLA-4, anti-PD-1 or anti-PD-L1 antibody checkpoint inhibitor. The primary patents of many of the current CTLA-4 and PD-1/PD-L1 checkpoint inhibitors face expiry over the course of the next several years.

“We are pleased that Ultimovacs’ innovative contributions to combination immunotherapies in cancer have been validated by the USPTO,” said Carlos de Sousa, Chief Executive Officer of Ultimovacs. “The company’s universal cancer vaccine UV1 is being assessed in combination with checkpoint inhibitors in five phase 2 trials for various cancers. The allowed claims will cover such combination treatments across these and other cancer indications and will extend proprietary use of the vaccine in combination with these checkpoint inhibitors until at least 2037.”

==ENDS==

About Ultimovacs
Ultimovacs is developing immune-stimulatory vaccines to treat a broad range of cancers. Ultimovacs’ lead universal cancer vaccine candidate UV1 targets human telomerase (hTERT), present in 85-90% of cancers in all stages of tumor growth. By directing the immune system to hTERT antigens, UV1 drives CD4 helper T cells to the tumor to activate an immune system cascade and increase anti-tumor responses. With a broad Phase II program, Ultimovacs aims to clinically demonstrate UV1’s impact in multiple cancer types in combination with other immunotherapies. Ultimovacs’ second technology approach, based on the proprietary Tetanus-Epitope-Targeting (TET) platform, combines tumor-specific peptides and adjuvant in the same molecule and entered Phase I studies in 2021.

For further information, please see www.ultimovacs.com or contact:

Carlos de Sousa, CEO
Email: carlos.desousa@ultimovacs.com
Phone: +47 908 92507

Anne Worsøe, Head of IR & Communication
Email: anne.worsoe@ultimovacs.com
Phone: +47 906 86815

Mary-Ann Chang, LifeSci Advisors
Email: mchang@lifesciadvisors.com
Phone: +44 7483 284 853

This information is considered to be inside information pursuant to the EU Market Abuse Regulation and is subject to the disclosure requirements pursuant to Section 5-12 in the Norwegian Securities Trading Act.

This stock exchange announcement was published by Joachim Midttun, Finance Manager at Ultimovacs ASA, on 22 April, 2022 at 8:00 CET


To view this piece of content from www.globenewswire.com, please give your consent at the top of this page.
To view this piece of content from ml-eu.globenewswire.com, please give your consent at the top of this page.

About GlobeNewswire by notified

GlobeNewswire by notified
GlobeNewswire by notified
One Liberty Plaza - 165 Broadway
NY 10006 New York

https://notified.com

GlobeNewswire by notified is one of the world's largest newswire distribution networks, specializing in the delivery of corporate press releases financial disclosures and multimedia content to the media, investment community, individual investors and the general public.

Subscribe to releases from GlobeNewswire by notified

Subscribe to all the latest releases from GlobeNewswire by notified by registering your e-mail address below. You can unsubscribe at any time.

Latest releases from GlobeNewswire by notified

RESULT OF RIKSBANK REVERSED AUCTIONS SEK MUNICIPAL BONDS24.5.2022 11:30:00 CEST | Press release

AuctionAuction resultsAuction date2022-05-24Maturity2025Tendered volume, SEK mln500 +/- 500Offered volume, SEK mln994Volume bought, SEK mln0Number of bids4Number of accepted bids0 QuarterQuarter 1Quarter 2Quarter 3Quarter 4Offered volume, SEK mln34450000Volume bought, SEK mln0000Number of bids2100Number of accepted bids0000Average yield, %----Lowest accepted yield, %----Highest yield, %----Accepted at lowest yield, %---- QuarterQuarter 1Quarter 2Quarter 3Quarter 4Offered volume, SEK mln150000Volume bought, SEK mln0000Number of bids1000Number of accepted bids0000Average yield, %----Lowest accepted yield, %----Highest yield, %----Accepted at lowest yield, %----

Nexstim Receives an Order for Two NBS Systems from a Finnish University Hospital24.5.2022 11:30:00 CEST | Press release

Press release, Helsinki, 24 May 2022 at 12:30 PM (EEST) Nexstim Receives an Order for Two NBS Systems from a Finnish University Hospital Nexstim Plc (NXTMH:HEX, NXTMS:STO) ("Nexstim" or "Company") has received an order for two NBS 5 systems from a university hospital in Finland. The customer is an experienced user of the Nexstim NBS 4 system, now acquiring the two new systems to replace the old system and to increase capacity. Nexstim’s NBS (Navigated Brain Stimulation) system is used, for example, in planning neurosurgery or radiation therapy after a patient has had a diagnosis of a brain tumor or other disorder. When the lesion is predicted to be close to functional areas of the brain—such as those responsible for speech production and limb movement —the brain maps generated with NBS can be invaluable when deciding the best, personalized treatment option for the patient. These specific NBS systems also include the software of an NBT® (Navigated Brain Therapy) system, allowing the sys

Sweegen Wins Stevia Reb M Patent Lawsuit Against PureCircle24.5.2022 11:04:00 CEST | Press release

Rancho Santa Margarita, Calif., May 24, 2022 (GLOBE NEWSWIRE) -- Sweegen, the global pioneer in wellness ingredient technologies and innovations, announced its victory against PureCircle in a stevia Rebaudioside M (Reb M) patent lawsuit. "Today's judgment vindicates Sweegen and affirms the company's position as an industry leader in innovative sweetener solutions," said Steven Chen, CEO of Sweegen. PureCircle, acquired by Ingredion in 2020, had filed the 2018 lawsuit against Sweegen in the U.S. District Court for the Central District of California, accusing Sweegen of infringing two PureCircle patents covering the manufacture of Reb M. The legal tide turned on PureCircle when Sweegen obtained a summary judgment that both of PureCircle's asserted patents are invalid. Since it is impossible to infringe an invalid patent, the court's invalidation of the asserted patents ends the infringement case against Sweegen at the U.S. District Court. "As a holder of core proprietary technologies of

Notification and Public Disclosure of Transactions by Person Discharging Managerial Responsibilities24.5.2022 11:00:00 CEST | Press release

Company Announcement No. 38/2022 Copenhagen, 24 May 2022 Notification and Public Disclosure of Transactions by Person Discharging Managerial Responsibilities 1. Information on the person discharging managerial responsibilities/person closely associated a) Name Anders Obel 2. Reason for the notification a) Position/title Member of the Board of Directors b) Initial notification/amendment Initial notification 3. Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor a) Name Scandinavian Tobacco Group A/S b) LEI code 5299003KG4JS99TRML67 4. Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted a) Description of the financial instrument, type of instrument Identification code Shares DK0060696300 – STG b) Nature of the transaction Sale of shares c) Price(s) and volume(s) Price(s)Volume(s)DKK 147.6 7,

Disclosure of voting rights for Chairman of the Board24.5.2022 10:44:47 CEST | Press release

Oslo, 24 May 2022. PCI Biotech Holding ASA ("PCI Biotech" or the "Company") issue this notification on behalf of its chairman, Hans Peter Bøhn. Hans Peter Bøhn is chairman of PCI Biotech and shall open the annual general meeting of the Company on 25 May 2022. Mr. Bøhn holds 123,662 shares, representing 0.3 per cent of the share capital of PCI Biotech. Mr. Bøhn has received powers of attorney to represent and vote for 7,234,249 additional shares. In total, Mr. Bøhn will represent and vote for 19.7 per cent of the share capital. A major part of the powers of attorney are without voting instructions. The powers of attorney are only valid at the annual general meeting on 25 May 2022. This information is subject to the disclosure requirements pursuant to section 4 -3, cf. section 5-12 of the Norwegian Securities Trading Act. Contact information: PCI Biotech Holding ASA, Ullernchausséen 64, N-0379 Oslo Ronny Skuggedal, CFO, rs@pcibiotech.no, Mobile: +47 9400 5757