GlobeNewswire

Idorsia selects Syneos Health as commercialization partner to launch daridorexant in the United States

Share

Idorsia selects Syneos Health as commercialization partner to launch daridorexant in the United States

  • Idorsia and Syneos Health collaborate to lead the transformation and modernization of the insomnia market in the US
  • Syneos Health selected for their robust customer-facing sales expertise to effectively reach the primary care market

Allschwil, Switzerland and Morrisville, N.C.– August 31, 2020
Idorsia Ltd (SIX: IDIA) and Syneos Health (Nasdaq: SYNH) today announced an innovative commercial relationship for the US commercialization of Idorsia’s daridorexant, a new dual orexin receptor antagonist being investigated for the treatment of insomnia. The strategic collaboration brings Idorsia’s lead investigational compound, daridorexant, and expertise in the science of the orexin system, together with Syneos Health’s robust customer-facing sales expertise and proven track record in launching new products in the US.

Simon Jose, Chief Commercial Officer of Idorsia, commented:
“Idorsia has discovered and developed a sleep medicine that, for the first time, has demonstrated in pivotal studies not only an improvement in sleep onset and sleep maintenance, but also in daytime functioning. With the scientific and clinical data we have generated, we believe that we have a unique drug with a potential to have a disruptive impact on the insomnia market once approved by health authorities. Although we will build the core capabilities needed to successfully launch our products ourselves, we are collaborating with Syneos Health on daridorexant in order to effectively reach the primary care market, which accounts for a large volume of insomnia prescriptions. By working together, I believe we can lead the transformation and modernization of the sleep market and bring daridorexant to the millions of people suffering from chronic insomnia.”

Syneos Health is the industry’s leading Contract Commercial Organization (CCO) and the longest-tenured US provider of outsourced sales teams, having launched more new products, created more sales teams and recruited more resources in the last five years than any other biopharmaceutical solutions company.  Syneos Health also leverages their unique Syneos One product development model, to accelerate product development and drive maximum asset value for customers.

Michelle Keefe, President, Syneos Health Commercial Solutions commented:
“We’re pleased to bring our best-in-class commercialization expertise to help daridorexant fulfill its full commercial potential.  We view Idorsia as an innovative biopharmaceutical company and have created an innovative, revenue-driven agreement to match, ultimately accelerating growth and reaching patients who need this treatment most.”

On August 28, 2020, data from the first successful pivotal study was presented at SLEEP 2020, the world’s largest meeting devoted entirely to clinical sleep medicine, and sleep and circadian research (press release). In April and July of 2020, Idorsia reported positive results in each of the two pivotal Phase 3 studies of daridorexant in patients with insomnia. More details and commentary can be found in the dedicated press releases (first study release), (second study release) and the investor webcasts (first study webcast), (second study webcast) which are available for replay on Idorsia’s corporate website: www.idorsia.com

Patricia Torr, President and General Manager of Idorsia US, commented:
“During the selection process we found ourselves aligned in our collective vision and strategy for daridorexant. The expertise of the Idorsia commercial organization combined with the sales and customer support capabilities of Syneos Health made our decision to move forward together very easy. Idorsia US now has its leadership team in place, a prime location for our US headquarters, and a pioneering collaboration, the key ingredients to successfully launch our commercial operations.”

Christian Tucat, President, Syneos One concluded:
“Advanced product development models that offer a modern approach to commercialization matter. Syneos One is looking to bring forward our suite of end-to-end solutions to develop our long-term relationship with Idorsia, starting with the US launch of daridorexant.”

Notes to the editor

About Insomnia
Insomnia is a condition of overactive wake signaling that can have a profound effect on the lives of patients. Insomnia can be defined as difficulty falling asleep and / or staying asleep, occurring at least three times a week for a minimum of three months. It is estimated that as many as one in ten people suffer from chronic insomnia and its impact is often underestimated; it can be a distressing condition that can impair quality of life, productivity and long-term health outcomes.

About Syneos Health
Syneos Health (Nasdaq:SYNH) is the only fully integrated biopharmaceutical solutions organization. Our Company, including a Contract Research Organization (CRO) and Contract Commercial Organization (CCO), is purpose-built to accelerate customer performance to address modern market realities. Our Company brings together approximately 24,000 clinical and commercial minds with the ability to support customers in more than 110 countries. Together we share insights, use the latest technologies and apply advanced business practices to speed our customers’ delivery of important therapies to patients. To learn more about how we are shortening the distance from lab to life®, visit syneoshealth.com

About Idorsia
Idorsia Ltd is reaching out for more - We have more ideas, we see more opportunities and we want to help more patients. In order to achieve this, we will develop Idorsia into a leading biopharmaceutical company, with a strong scientific core. Headquartered in Switzerland - a biotech-hub of Europe - Idorsia is specialized in the discovery and development of small molecules, to transform the horizon of therapeutic options. Idorsia has a broad portfolio of innovative drugs in the pipeline, an experienced team, a fully-functional research center, and a strong balance sheet – the ideal constellation to bringing R&D efforts to business success. Idorsia was listed on the SIX Swiss Exchange (ticker symbol: IDIA) in June 2017 and has over 800 highly qualified specialists dedicated to realizing our ambitious targets. With its US Commercial Operations based in the Philadelphia region, Idorsia is committed to meet the changing needs of healthcare professionals, patients and their families.  The core of what we do is to bring creative solutions to the market based on our science and data.

For further information, please contact

For Idorsia:
Andrew C. Weiss
Senior Vice President, Head of Investor Relations & Corporate Communications
Idorsia Pharmaceuticals Ltd, Hegenheimermattweg 91, CH-4123 Allschwil
+41 58 844 10 10
www.idorsia.com

For Syneos Health:
Investor Relations
Ronnie Speight
Senior Vice President, Investor Relations
+1 919 745 2745
investor.relations@syneoshealth.com

Press/Media:
Danielle DeForge
Executive Director, External Communications
+1 202 210 5992
danielle.deforge@syneoshealth.com

The above information contains certain "forward-looking statements", relating to the company's business, which can be identified by the use of forward-looking terminology such as "estimates", "believes", "expects", "may", "are expected to", "will", "will continue", "should", "would be", "seeks", "pending" or "anticipates" or similar expressions, or by discussions of strategy, plans or intentions. Such statements include descriptions of the company's investment and research and development programs and anticipated expenditures in connection therewith, descriptions of new products expected to be introduced by the company and anticipated customer demand for such products and products in the company's existing portfolio. Such statements reflect the current views of the company with respect to future events and are subject to certain risks, uncertainties and assumptions. Many factors could cause the actual results, performance or achievements of the company to be materially different from any future results, performances or achievements that may be expressed or implied by such forward-looking statements. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those described herein as anticipated, believed, estimated or expected.

Attachment

About GlobeNewswire

GlobeNewswire
GlobeNewswire
One Liberty Plaza - 165 Broadway
NY 10006 New York

https://globenewswire.com

GlobeNewswire is one of the world's largest newswire distribution networks, specializing in the delivery of corporate press releases financial disclosures and multimedia content to the media, investment community, individual investors and the general public.

Subscribe to releases from GlobeNewswire

Subscribe to all the latest releases from GlobeNewswire by registering your e-mail address below. You can unsubscribe at any time.

Latest releases from GlobeNewswire

Result of Riksbank´s purchases of Commercial Paper25.11.2020 10:00:00 CETPress release

Auction date201125 Requested volume, SEK mln4,000 Credit rating class1Term3MFixed purchase rate0.45 %Total bid amount, SEK mln0,000Prel. accepted volume, SEK mln0,000Percentage alloted0.00 %Number of bids0 Credit rating class1Term6MFixed purchase rate0.55 %Total bid amount, SEK mln0,000Prel. accepted volume, SEK mln0,000Percentage alloted0.00 %Number of bids0 Credit rating class2Term3MFixed purchase rate0.75 %Total bid amount, SEK mln0,000Prel. accepted volume, SEK mln0,000Percentage alloted0.00 %Number of bids0 Credit rating class2Term6MFixed purchase rate0.85 %Total bid amount, SEK mln0,000Prel. accepted volume, SEK mln0,000Percentage alloted0.00 %Number of bids0

ZetaDisplay lanserar nästa generations globala mjukvaruplattform25.11.2020 08:30:00 CETPressemelding

Malmö - ZetaDisplay AB (publ) (Nasdaq Stockholm: ZETA) lanserar sin egenutvecklade nästa generations mjukvaruplattform för schemaläggning och distribution av molnbaserat innehåll. Den uppgraderade mjukvaran ZetaDisplay Engage kommer att implementeras med omedelbar verkan hos koncernens internationella kundbas. "Trots osäkerheten på marknaden har vi fortsatt att investera i vårt mjukvaru- och tjänsteerbjudande under 2020 för att accelerera tillväxten", säger VD Per Mandorf. " Efter 5 000 mantimmar av utveckling är vi nu redo att lansera den senaste versionen av vårt content management system som styr våra kunders Digital Signage-installationer", fortsätter Mandorf. Uppgraderingen kommer att ske i två faser där det inledande fokuset kommer att ligga på ett toppmodernt användargränssnitt tillsammans med en framtidssäker molnbaserad lösning. Plattformen erbjuder ett brett utbud av funktionalitet, är lätt att ansluta till kundernas digitala ekosystem och kan även hantera livedata. Parallell

ArcAroma AB: 201125 Samarbetsavtal med OptiFreeze ökar möjligheten till accelerad tillväxt25.11.2020 08:30:00 CETPressemelding

Pressmeddelande 2020-11-25 ArcAroma och OptiFreeze har idag tecknat ett utvärderingsavtal gällande samarbete. Syftet med avtalet är att utvärdera möjligheten till framtida gemensamma projekt för livsmedelsapplikationer. ArcAromas organisation kommer dessutom stödja OptiFreeze i deras marknadsexpansion för snittblommor. ArcAroma har under de senaste åren mer och mer fokuserat på livsmedelssektorn. Bolaget ser en stor potential i denna globala marknad och har olika applikationer under marknadsutveckling och nya i utvecklingsfas. ArcAromas ledning och styrelse ser att ett fördjupat samarbete med OptiFreeze erbjuder en stor potential att skapa ett starkare och konkurrenskraftigare ArcAroma inom livsmedelsteknik. Det tekniska och vetenskapliga kunnandet i respektive bolag är komplementära. ArcAroma har redan ett starkt fokus på olika livsmedel och här skulle OptiFreeze gedigna grundforskning och höga kompetens inom metodutveckling kunna bidra till att bredda applikationsportföljen. ArcAroma

ZetaDisplay launches next generation global software platform25.11.2020 08:30:00 CETPress release

Malmö - ZetaDisplay AB (publ) (Nasdaq Stockholm: ZETA) announces the launch of its next-generation software platform for proprietary, cloud-based content scheduling and distribution. The upgraded ZetaDisplay Engage will be implemented with immediate effect with the Group’s international customer base. “Despite the uncertainty in the market, we have continued to invest in our software and services offer during 2020 to accelerate growth”, says CEO Per Mandorf. “After 5,000 manhours of development we are now ready to launch the latest version of our content management system steering our customers’ Digital Signage networks”, Mandorf continues. The upgrade will happen in two phases where the initial focus will be on a state-of-the-art user interface together with a future-proof cloud-based solution. The platform offers a broad range of functionality, is easily connectable to customers’ digital ecosystem and can also handle live data. In parallel, a new standard service catalogue has been l

Avance Gas Holding Ltd Reports Unaudited Results for the Third Quarter of 202025.11.2020 08:00:00 CETPress release

BERMUDA, 25 November 2020 – Avance Gas Holding Ltd (OSE: AVANCE) today reported unaudited results for the third quarter 2020. HIGHLIGHTS An achieved time charter equivalent (TCE) rate of $23,283 on a discharge to discharge basis and $21,524/day on the basis of IFRS 15 accounting standard, compared to $28,453/day and $28,932/day in Q2 2020 respectively.The TCE rates in Q3 reflects ballast cost of approx. $4,000/day, corresponding to an adjusted TCE rate of $27,283 in Q3. The ballast cost will recover into the following quarter.Daily operating expenses (OPEX) were $9,256/day, compared to $8,576/day in Q2 2020. OPEX was impacted by change of technical manager and Covid-19 related crew change expense representing approx. $900/day in Q3.A&G expenses were $727/day, up from $608/day in Q2.Secured funding for predelivery CAPEX of newbuilding program through two transactions In September, the sale of the 2003-built VLGC Avance was successfully completed. Following repayment of debt, the transac

Incap Corporation: Incap Group’s Business Review for January–September 2020: Back on track with good growth and profitability25.11.2020 07:30:00 CETPress release

Incap Corporation Stock Exchange Release Business Review Q3 2020 25 November 2020 at 8.30 a.m. (EET) Incap Group’s Business Review for January–September 2020: Back on track with good growth and profitability July–September 2020 highlights The revenue of the third quarter amounted to EUR 28.1 million, showing an increase of 59.9% (7– 9/2019: EUR 17.6 million).Excluding revenue from AWS Electronics Group acquired in January 2020, the revenue increased organically by 10.7%.Adjusted EBIT was EUR 3.6 million (EUR 2.4 million), corresponding to 12.9% of revenue (13.7%).AWS Electronics Group acquisition related purchase price allocation (PPA) amortisation amounted to EUR 0.4 million (EUR 0.0 million) and non-recurring costs were EUR 0.0 million (EUR 0.2 million). Operating profit (EBIT) was EUR 3.3 million (EUR 2.2 million), an increase of 46.0%, corresponding to 11.6% of revenue (12.7%).Net profit for the period was EUR 2.4 million (EUR 1.8 million), an increase of 33.7%.In November 2020, In