Incyte Announces New Data from across its Oncology Portfolio to be Presented at ESMO Congress 2023
Incyte (Nasdaq:INCY) today announced that abstracts featuring new data from its oncology portfolio will be presented at the upcoming European Society for Medical Oncology (ESMO) Congress 2023, held October 20-24 in Madrid.
"We look forward to sharing data from our oncology portfolio with the scientific community at this year’s ESMO Congress,” said Steven Stein, M.D., Chief Medical Officer, Incyte. “Presentations, including results from studies of retifanlimab and capmatinib, focused on patients with endometrial cancer, Merkel cell carcinoma and non-small cell lung cancer, showcase our continued efforts to pursue innovative therapies for patients with cancer.”
Key abstracts from Incyte-sponsored and partner programs include:
Retifanlimab in Patients with Recurrent Microsatellite Instability-High (MSI-H) or Deficient Mismatch Repair (dMMR) Endometrial Cancer: Final Results from the POD1UM-101 Study (Cohort H) (Abstract #755P. Topic: Gynecological Cancers. Sunday, October 22, 6:00 a.m. – 7:00 a.m. ET)
Updated Results from POD1UM-201: A Phase 2 Study of Retifanlimab in Patients with Advanced or Metastatic Merkel Cell Carcinoma (MCC) (Abstract #1146P. Topic: Melanoma and Other Skin Tumors. Sunday, October 22, 6:00 a.m. – 7:00 a.m. ET)
Efficacy of Capmatinib Compared to Standard of Care for German Patients with Locally Advanced or Metastatic NSCLC Harboring METex14 Mutations: Results from the RECAP Study1(Abstract #1383P. Topic: NSCLC, Metastatic. Monday, October 23, 6:00 a.m. – 7:00 a.m. ET)
Capmatinib vs Docetaxel as Second- or Third-line (2/3L) Therapy in Patients (Pts) with METex14-Mutated Advanced NSCLC (aNSCLC): The GeoMETry-3 Trial1(Abstract #1391P. Topic: NSCLC, Metastatic. Monday, October 23, 6:00 a.m. – 7:00 a.m. ET)
For full session details and data presentation listings, please see the ESMO Congress 2023 (https://www.esmo.org/meeting-calendar/esmo-congress-2023/programme) online program.
About Zynyz™ (retifanlimab-dlwr)
Zynyz (retifanlimab-dlwr), is an intravenous PD-1 inhibitor indicated in the U.S. for the treatment of adult patients with metastatic or recurrent locally advanced Merkel cell carcinoma (MCC). This indication is approved under accelerated approval based on tumor response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials.
Zynyz is marketed by Incyte in the U.S. In 2017, Incyte entered into an exclusive collaboration and license agreement with MacroGenics, Inc. for global rights to retifanlimab.
Zynyz is a trademark of Incyte.
About Tabrecta® (capmatinib)
Tabrecta is approved in several countries including the EU, United States (U.S.), Japan and Switzerland. It is the number one prescribed targeted therapy for patients with advanced non-small cell lung cancer (NSCLC) with alterations leading to mesenchymal-epithelial transition factor gene exon 14 (METex14) skipping globally2.
Tabrecta is a kinase inhibitor that targets mesenchymal-epithelial transition (MET). Tabrecta was discovered by Incyte and licensed to Novartis in 2009. Under the agreement, Incyte granted Novartis worldwide exclusive development and commercialization rights to capmatinib and certain back-up compounds in all indications.
Incyte is a Wilmington, Delaware-based, global biopharmaceutical company focused on finding solutions for serious unmet medical needs through the discovery, development and commercialization of proprietary therapeutics. For additional information on Incyte, please visit Incyte.com and follow @Incyte.
Except for the historical information set forth herein, the matters set forth in this press release, including statements regarding the presentation of data from Incyte’s clinical development pipeline, whether or when any development compounds or combinations will be approved or commercially available for use in humans anywhere in the world outside of the already approved indications in specific regions and Incyte’s goal of improving the lives of patients, contain predictions, estimates and other forward-looking statements.
These forward-looking statements are based on Incyte’s current expectations and subject to risks and uncertainties that may cause actual results to differ materially, including unanticipated developments in and risks related to: unanticipated delays; further research and development and the results of clinical trials possibly being unsuccessful or insufficient to meet applicable regulatory standards or warrant continued development; the ability to enroll sufficient numbers of subjects in clinical trials; determinations made by the FDA, EMA, and other regulatory authorities; the efficacy or safety of Incyte and its partners’ products; the acceptance of Incyte and its partners’ products in the marketplace; market competition; sales, marketing, manufacturing and distribution requirements; and other risks detailed from time to time in Incyte’s reports filed with the Securities and Exchange Commission, including its annual report and its quarterly report on Form 10-Q for the quarter ended June 30, 2023. Incyte disclaims any intent or obligation to update these forward-looking statements.
1 Novartis-sponsored abstract
2 Data on file
To view this piece of content from cts.businesswire.com, please give your consent at the top of this page.
About Business Wire
(c) 2018 Business Wire, Inc., All rights reserved.
Business Wire, a Berkshire Hathaway company, is the global leader in multiplatform press release distribution.
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
Capcom Reveals Dragon’s Dogma 2 Scheduled to Launch March 22, 2024!29.11.2023 02:00:00 CET | Press release
Capcom Co., Ltd. (TOKYO:9697) today announced that Dragon’s Dogma 2, the latest game in the Dragon’s Dogma series, is scheduled to be released on March 22, 2024. With the launch of Dragon’s Dogma 2, Capcom closes out a stellar year of major title releases for its 2023 fiscal year. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20231128898951/en/ Dragon's Dogma 2 is a single player, narrative driven action-RPG and the latest title in the Dragon’s Dogma series. The game features intricately crafted, gorgeous visuals powered by Capcom’s proprietary RE ENGINE that elevate its unique gameplay experience to provide a truly immersive fantasy world sure to delight both newcomers as well as long-time fans of the series. (Graphic: Business Wire) Dragon’s Dogma 2 is the latest title in the series, and the first mainline entry since the original Dragon’s Dogma was released in 2012. The game is being developed on Capcom’s proprietary RE EN
Rocket Software to Acquire OpenText’s Application Modernization and Connectivity Business28.11.2023 22:20:00 CET | Press release
Rocket Software, Inc. (“Rocket Software”), a global technology leader driving modernization for the world’s largest companies, today announced it has signed a definitive agreement to acquire the Application Modernization and Connectivity business (AMC) of OpenText (NASDAQ: OTEX), (TSX: OTEX), which was formerly part of Micro Focus. The total purchase price is $2.275B. For decades, Rocket Software has been the partner solving complex IT challenges for the largest and most innovative organizations, across infrastructure, data, and applications. Rocket Software’s hybrid cloud strategy empowers customers to optimize their application portfolio wherever they are in their modernization journey, enabling them to bridge the gap to modern use cases without disrupting their mission-critical operations. This approach allows organizations to benefit from the mainframe's security and dependability while also taking advantage of powerful analytics tools in the cloud. AMC has been a leader in applica
NetApp and AWS Deliver a Nine Times Performance Increase for Amazon FSx for NetApp ONTAP28.11.2023 22:05:00 CET | Press release
NetApp® (NASDAQ: NTAP), the intelligent data infrastructure company, announced at re:Invent, scale-out FSx for ONTAP® file systems through its collaboration with AWS. Scale-out file systems offer up to nine times higher storage performance compared to existing file systems, enabling customers to run high-performance applications on AWS more quickly and efficiently. FSx for ONTAP enables customers to use ONTAP’s data management features for a wide variety of workloads, such as user and application file shares, relational databases (SAP HANA), data stores for VMware cloud on AWS and backup and disaster recovery. With the new enhancements, customers can now use FSx for ONTAP for a broader range of higher-performance use cases, such as high-performance computing (HPC), electronic design automation (EDA), visual effects (VFX) and film editing, life sciences, seismic analysis, machine learning, and generative AI. Organizations of all sizes are migrating on-premises workloads to AWS or deploy
Varberg Energi Selects Hansen to Power Intraday Trading28.11.2023 20:50:00 CET | Press release
Hansen Technologies (ASX:HSN), a leading global provider of software and services to the energy, water and communications industries, is pleased to announce Varberg Energi, a Swedish energy company, as a new Hansen customer. Varberg Energi, which has recently added physical-trading operations and balance responsibility to its services, will leverage Hansen Trade to enable this. The intraday trading solution within Hansen Trade will allow Varberg Energi to automate intraday trading operations and balance management. With Hansen Trade as part of its everyday operating infrastructure, Varberg Energi will be able to take advantage of physical trading operations without the need to spend significant time and effort on manual operations. Jens Nordberg, Head of Energy Trading, Varberg Energi, commented: “We have recently made a strategic decision to insource physical-trading operations and balance responsibility. Combined with our flexibility portfolio, we believe that this will create the ri
Abu Dhabi’s Advanced Technology Research Council launches ‘AI71’: New AI Company Pioneering Decentralised Data Control for Companies & Countries28.11.2023 18:16:00 CET | Press release
In an era of rapid advancements across artificial intelligence (AI), Abu Dhabi’s Advanced Technology Research Council (ATRC) is making yet another bold stride with the launch of its new AI company, AI71. The entity builds on the Technology Innovation Institute’s (TII) Falcon generative AI models and will focus on multi-domain specializations while offering unprecedented AI data control options for companies and countries looking to self-host for greater privacy. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20231128549220/en/ H.H. Sheikh Khaled bin Mohamed bin Zayed Al Nahyan, Crown Prince of Abu Dhabi and Chairman of the Abu Dhabi Executive Council launches AI71 along with H.E Faisal Al Bannai, Secretary General, Advanced Technology Research Council (Photo: AETOSWire) The new AI powerhouse was launched by H.H. Sheikh Khaled bin Mohamed bin Zayed Al Nahyan, Crown Prince of Abu Dhabi and Chairman of the Abu Dhabi Executive Cou